反应 #57818

反应方程式

(2-amino-4,5-difluoro-phenyl)-pyridin-3-yl-methanone

4-bromo-benzenesulfonyl chloride

→

title compound

4-Bromo-N-[4,5-difluoro-2-(pyridine-3-carbonyl)-phenyl]-benzenesulfonamide

溶剂

pyridine

反应条件

后处理

1. 1
   其他Purification on silica gel with flash column chromatography
2. 2
   其他yielded light orange solid

实验过程

The title compound was prepared according to the general procedures for the synthesis of N-Aryl-benzenesulfonamides previously described using (2-amino-4,5-difluoro-phenyl)-pyridin-3-yl-methanone 1 g (4.27 mmol) and 4-bromo-benzenesulfonyl chloride 1.15 g (4.27 mmol) with stirring in 20 ml pyridine. Purification on silica gel with flash column chromatography yielded light orange solid

来源