反应 #5741

反应方程式

n-dodecyl alcohol

chlorosulfonyl isocyanate

→

white solid

收率 101.6%

Dodecyl(chlorosulfonyl)carbamate

收率 101.6%

溶剂

Et2O

Et2O

反应条件

后处理

1. 1
   浓缩concentrated in vacuo
2. 2
   其他The residue was triturated with cold hexanes
3. 3
   其他to give a white solid
4. 4
   过滤collected by filtration

实验过程

A solution of n-dodecyl alcohol (10.7 g, 57.4 mmoles) in 100 mL Et2O was added dropwise to a solution of chlorosulfonyl isocyanate (5.0 mL, 57.4 mmoles) in 100 mL Et2O at ~15° C. under an atmosphere of N2. The resulting mixture was stirred for 2 hours and concentrated in vacuo. The residue was triturated with cold hexanes to give a white solid and collected by filtration to give 19.12 g of a white solid, mp 62°-63° C.

来源