反应 #56581

反应方程式

2,3,5-Triiodobenzoyl chloride

1-(z,z,z-octadeca-6,9,12-trienoyloxy)-3-hydroxypropane

triethylamine

→

1-(2,3,5-triiodobenzoyloxy)-3-(z,z,z-octadeca-6,9,12-trienoyloxy)propane

溶剂

methylene chloride

反应条件

后处理

1. 1
   浓缩The mixture was concentrated
2. 2
   其他purified by flash chromatography (ethyl acetate/hexane)

实验过程

2,3,5-Triiodobenzoyl chloride (1.54 g, 3.08 mmol) was added to a mixture of 1-(z,z,z-octadeca-6,9,12-trienoyloxy)-3-hydroxypropane (1 g, 2.97 mmol) and triethylamine (1 ml) in methylene chloride (80 ml) and the resulting mixture stirred overnight at room temperature under nitrogen. The mixture was concentrated and purified by flash chromatography (ethyl acetate/hexane) to yield 1-(2,3,5-triiodobenzoyloxy)-3-(z,z,z-octadeca-6,9,12-trienoyloxy)propane.

来源