反应 #5610

反应方程式

5-benzyloxy-2-vinyl-4-pyridone

pyrrolidine

→

5-benzyloxy-2-[2-(1-pyrrolidinyl)ethyl]4-pyridone

溶剂

tetrahydrofuran

diisopropyl ether

反应条件

后处理

1. 1
   温度was heated
2. 2
   温度refluxed for an hour
3. 3
   温度The mixture was cooled
4. 4
   过滤the resulting precipitate was collected by filtration
5. 5
   洗涤washed with diisopropyl ether
6. 6
   其他air-dried at ambient temperature

实验过程

A mixture of 5-benzyloxy-2-vinyl-4-pyridone (2.90 g) and pyrrolidine (5.33 ml) was heated and refluxed for an hour. The mixture was cooled and diluted with tetrahydrofuran (20 ml) and diisopropyl ether (80 ml). After being stirred for an hour at ambient temperature, the resulting precipitate was collected by filtration, washed with diisopropyl ether and air-dried at ambient temperature to give 5-benzyloxy-2-[2-(1-pyrrolidinyl)ethyl]4-pyridone (3.79 g).

来源