反应 #55828

ord-c0b4079ea0374705a17d25381f895c0e

反应条件

详细条件
See reaction.notes.procedure_details.

实验过程

Methyl 5-benzyl-4-oxazolecarboxylate is reduced with lithium aluminium hydride in tetrahydrofuran to give 5-benzyl-4-hydroxymethyloxazole, which by reacting with thionyl chloride is converted to 5-benzyl-4-chloromethyloxazole.

来源

DOI: 10.6084/m9.figshare.5104873.v1专利: US04221802uspto-grants-1980_09