反应 #556858

反应方程式

product

2-amino-4-(4-chlorophenyl)phthalazin-1(2H)-one

2-(benzo[d][1,3]dioxol-5-yl)acetic acid

→

title compound

2-(1,3-benzodioxol-5-yl)-N-[4-(4-chlorophenyl)-1-oxophthalazin-2(1H)-yl]acetamide

反应条件

实验过程

The product from Example 86A and 2-(benzo[d][1,3]dioxol-5-yl)acetic acid were treated using a method similar to that described in Example 57 to give the title compound. 1H NMR (500 MHz, DMSO-d6/D2O) δ 8.41 (m, 1H), 8.01-7.95 (m, 2H), 7.72 (m, 1H), 7.63 (m, 4H), 6.96 (d, J=1.6, 1H), 6.88 (d, J=7.9, 1H), 6.84 (dd, J=8.0, 1.6, 1H), 5.99 (s, 2H), 3.61 (s, 2H); MS (APCI+) M/Z 434 (M+H)+.

来源