反应 #55563

反应方程式

9-ethylenedioxy-15-keto-19-methyl-prost-13,18-dienoic acid, methyl ester

→

9-ethylenedioxy-15-keto-19-methyl-prost-18-enoic acid, methyl ester

收率 88.2%

溶剂

ethanol

反应条件

后处理

1. 1
   洗涤washed with ethanol
2. 2
   其他is hydrogenated at room temperature under pressure
3. 3
   其他After absorption of the theoretical quantity of hydrogen the catalyzer
4. 4
   其他is separated by filtration
5. 5
   其他the solvent evaporated in vacuo

实验过程

To the solution of 4.4 g of 9-ethylenedioxy-15-keto-19-methyl-prost-13,18-dienoic acid, methyl ester, in ethanol (60 ml.) are added 0.8 g of Raney-nickel washed with ethanol and the mixture is hydrogenated at room temperature under pressure. After absorption of the theoretical quantity of hydrogen the catalyzer is separated by filtration and the solvent evaporated in vacuo, to yield 3.9 g of 9-ethylenedioxy-15-keto-19-methyl-prost-18-enoic acid, methyl ester.

来源