反应 #554567

反应方程式

Phosphorus oxychloride

dimethylaniline

phenanthridine

→

9-chlorophenanthridine

收率 96.0%

溶剂

H2O

反应条件

后处理

1. 1
   温度by refluxing for 3 hours
2. 2
   萃取the obtained solid was extracted with chloroform
3. 3
   干燥by drying with sodium sulfate
4. 4
   过滤After filtration
5. 5
   其他the filtrate was evaporated to dryness under reduced pressure
6. 6
   其他The obtained solid was purified by column chromatography (eluent: chloroform) (amount: 2.1 g, yield: 96%)

实验过程

Phosphorus oxychloride (15 ml) and dimethylaniline (0.63 ml) were added to phenanthridine (2.0 g), followed by refluxing for 3 hours. The solution was poured into H2O to generate a solid, and the obtained solid was extracted with chloroform, followed by drying with sodium sulfate. After filtration, the filtrate was evaporated to dryness under reduced pressure. The obtained solid was purified by column chromatography (eluent: chloroform) (amount: 2.1 g, yield: 96%).

来源