反应 #55154

ord-b46e15a44c7d4b3e9dc0349e9204fa3c

反应条件

详细条件
See reaction.notes.procedure_details.

实验过程

Methyl 5-benzyl-4-oxazolecarboxylate is reduced with lithium aluminium hydride in tetrahydrofuran to give 5-benzyl-4-hydroxymethyloxazole, which on reaction with thionyl chloride is converted to 5-benzyl-4-chloromethyloxazole.

来源

DOI: 10.6084/m9.figshare.5104873.v1专利: US04151288uspto-grants-1979_04