反应 #54991

反应方程式

2-(4'-chloro-4-biphenylyl)-6-(tetrahydropyran-2-yloxy)-3-hexyn-2-ol

HCl

→

2-(4'-chloro-4-biphenylyl)-3-hexyn-2,6-diol

溶剂

dioxane

反应条件

实验过程

To 38.5 g. of 2-(4'-chloro-4-biphenylyl)-6-(tetrahydropyran-2-yloxy)-3-hexyn-2-ol in 250 ml. of dioxane, is added dropwise with ice cooling, 100 ml. of 1 N HCl. The resulting mixture is stirred 12 hours more at 0°. After the usual work up, 2-(4'-chloro-4-biphenylyl)-3-hexyn-2,6-diol, m.p. 105°, is obtained.

来源