反应 #543562

反应方程式

4-Hexadecanyl phosphate

NaOH

→

final product

收率 93.5%

4-Hexadecanyl Monosodium Phosphate

收率 93.5%

溶剂

ethanol

反应条件

后处理

1. 1
   其他evaporated
2. 2
   workup.ADDITIONEthanol (2×150 ml) was added
3. 3
   其他evaporated
4. 4
   workup.ADDITIONEther (2×100 ml) was added
5. 5
   其他evaporated
6. 6
   其他The obtained solid was triturated with acetone (100 ml)
7. 7
   其他dried under 1 mm. Hg atmosphere overnight

实验过程

4-Hexadecanyl phosphate (3.13 g, 0.0097 mol) was dissolved in ethanol (150 ml). NaOH (0.37 g, 0.0092 mol) was added and the mixture was stirred for 48 hrs and then evaporated. Ethanol (2×150 ml) was added and evaporated. Ether (2×100 ml) was added and evaporated. The obtained solid was triturated with acetone (100 ml) and dried under 1 mm. Hg atmosphere overnight. 2.98 g of final product was obtained. Yield 87%.

来源