反应 #543559

反应方程式

N-(3-(4-arsenosophenylcarbamoylmethylthio)propanoyl)-L-aspartic acid

triphenylphosphine

disodium N-(3-mercaptopropanoyl)-L-glutamate

bicarbonate

→

N-(3-(4-arsenosophenylcarbamoylmethylthio)propanoyl)-L-glutamic acid

溶剂

DMSO

DMSO

DMSO

反应条件

后处理

1. 1
   其他before leaving overnight
2. 2
   浓缩The active concentration of trivalent arsenic

实验过程

The procedure used was the same as for N-(3-(4-arsenosophenylcarbamoylmethylthio)propanoyl)-L-aspartic acid, using 2.63 mL (184 μmol) of 70.0 mM BRAO in DMSO, the disulfide of disodium N-(3-mercaptopropanoyl)-L-glutamate (0.61 g), 0.5 M bicarbonate buffer, pH 9 (10.52 mL, 5.3 mmol), and 0.69 M triphenylphosphine in DMSO (1.7 mL, 1.2 mmol). In this case, DMSO (2 mL) was added to the precipitated mixture before leaving overnight. The active concentration of trivalent arsenic was found to be 15.4 mM (10.3 mL of solution).

来源