反应 #54289

反应方程式

3-(4-chlorobenzoyl)-benzeneacetic acid

thionyl chloride

→

3-(4-chlorobenzoyl)-benzeneacetic acid chloride

反应条件

后处理

1. 1
   温度to reflux
2. 2
   其他excess thionyl chloride was removed under reduced pressure
3. 3
   workup.DISSOLUTIONThe residue was dissolved in benzene
4. 4
   其他the solution was evaporated to dryness under reduced pressure
5. 5
   workup.DISSOLUTIONThe residue was dissolved in 50ml of anhydrous benzene

实验过程

A solution of 8.235 g of 3-(4-chlorobenzoyl)-benzeneacetic acid in 20 ml of thionyl chloride was heated to reflux and then excess thionyl chloride was removed under reduced pressure. The residue was dissolved in benzene and the solution was evaporated to dryness under reduced pressure. The residue was dissolved in 50ml of anhydrous benzene to obtain a solution of 3-(4-chlorobenzoyl)-benzeneacetic acid chloride which was used as is for the next step.

来源