反应 #53670

ord-326bba7b2f4f49ab91dc51bf762c3c23

反应方程式

Nc1n[nH]c2ccc([N+](=O)[O-])cc12
3-amino-5-nitro-1H-indazole
CS(=O)(=O)Cl
methylsulfonyl chloride
→
CS(=O)(=O)Nc1n[nH]c2ccc([N+](=O)[O-])cc12
3-methylsulfonylamino-5-nitro-1H-indazole
收率 84.4%

反应物

Nc1n[nH]c2ccc([N+](=O)[O-])cc12
3-amino-5-nitro-1H-indazole
CS(=O)(=O)Cl
methylsulfonyl chloride

试剂

无

溶剂

c1ccncc1
pyridine

反应条件

详细条件
See reaction.notes.procedure_details.

实验过程

3-Methylsulfonylamino-5-nitro-1H-indazole can be obtained as described in Example 2 from 0.7 g of 3-amino-5-nitro-1H-indazole, 23 ml of pyridine and 0.455 g of methylsulfonyl chloride. 0.85 g of 3-methylsulfonylamino-5-nitro-1H-indazole is thus obtained in the form of an orange powder used as it is in the following step.

来源

DOI: 10.6084/m9.figshare.5104873.v1专利: US06858638B2uspto-grants-2005_02