反应 #53669

反应方程式

ammonia

3-methylsulfonylamino-5-nitro-1H-indazole

ethanol

→

5-amino-3-methylsulfonylamino-1H-indazole

收率 44.2%

溶剂

water

反应条件

实验过程

5-Amino-3-methylsulfonylamino-1H-indazole can be obtained as described in Example 4 from 256 mg of 3-methylsulfonylamino-5-nitro-1H-indazole, 10 ml of ethanol, 2 g of ferrous sulfate, 3.2 ml of water and 2.4 ml of 32% aqueous ammonia. 0.1 g of 5-amino-3-methylsulfonylamino-1H-indazole is thus obtained in the form of an oil used as it is in the following step.

来源