反应 #53133

ord-14660ef7db7c4a9aa77eb24b2026c98d

反应方程式

CC(C)(C)OC(=O)c1ccc(CN2C(=O)c3ccccc3C2=O)cc1
tert.butyl 4-phthalimidomethyl-benzoate
→
O=C(O)c1ccc(CN2C(=O)c3ccccc3C2=O)cc1
4-phthalimidomethyl-benzoic acid

反应物

CC(C)(C)OC(=O)c1ccc(CN2C(=O)c3ccccc3C2=O)cc1
tert.butyl 4-phthalimidomethyl-benzoate

试剂

无

溶剂

O=C(O)C(F)(F)F
trifluoroacetic acid

反应条件

详细条件
See reaction.notes.procedure_details.

实验过程

337 mg (1.0 mmol) of tert.butyl 4-phthalimidomethyl-benzoate are stirred in 3 ml of trifluoroacetic acid for 45 minutes at ambient temperature. Then the solvent is eliminated in vacuo.

来源

DOI: 10.6084/m9.figshare.5104873.v1专利: US06855710B2uspto-grants-2005_02