反应 #528085

反应方程式

2-amino-3-cyano-5-[(4-trifluoromethylphenyl)ethynyl]pyrazine

chloroformamidine hydrochloride

→

2,4-diamino-6-[1-chloro-2-(4-trifluoromethylphenyl)ethenyl]pteridine

溶剂

diglyme

反应条件

后处理

1. 1
   其他This compound is prepared in a manner analogous to that of Step C of Example 7

实验过程

This compound is prepared in a manner analogous to that of Step C of Example 7, using 2.9 grams (0.009 mole) of 2-amino-3-cyano-5-[(4-trifluoromethylphenyl)ethynyl]pyrazine and 0.9 gram (0.009 mole) of chloroformamidine hydrochloride in 20 mL of diglyme, yielding 2,4-diamino-6-[1-chloro-2-(4-trifluoromethylphenyl)ethenyl]pteridine.

来源