反应 #51459

反应方程式

5-chlorocarbonylphthalid

dimethylamine

→

5-(N,N-dimethylcarbamyl)phthalid

溶剂

THF

反应条件

后处理

1. 1
   其他THF is evaporated off in vacuo
2. 2
   其他precipitated crystals
3. 3
   其他are filtred off at 5° C.
4. 4
   洗涤washed with water (100 ml)

实验过程

A solution of 5-chlorocarbonylphthalid (32 g, 0.16 mole) in THF (300 ml) is added to dimethylamine (40% v/v in water, 300 ml) and ice (100 g). The mixture is stirred for 1 hour. THF is evaporated off in vacuo and precipitated crystals are filtred off at 5° C. and washed with water (100 ml).

来源