反应 #502073

反应方程式

4-[(1,5-dimethylhexyl)oxy]butan-1-ol

PCC

sodium acetate

stavox

→

desired product

收率 82.0%

4-[(1,5-dimethylhexyl)oxy]butanal

收率 82.0%

溶剂

dichloromethane

反应条件

后处理

1. 1
   其他A 250 mL 3-necked flask was equipped with a thermocouple pocket, magnetic stirrer and condenser
2. 2
   workup.STIRRINGThe reaction was stirred for 3 hrs at room temperature

实验过程

A 250 mL 3-necked flask was equipped with a thermocouple pocket, magnetic stirrer and condenser. PCC (13.9 g, 0.64 mols), sodium acetate (1.22 g, 0.015 mol), stavox (0.01 g) and dichloromethane (100 mL) were added to the flask. 4-[(1,5-dimethylhexyl)oxy]butan-1-ol (10.0 g, 0.05 mol) was added over 5 minutes with stirring. The reaction was stirred for 3 hrs at room temperature. After this time the reaction mixture contained ca. 82% of the desired product (RPA GC).

来源