反应 #50194

反应方程式

benzyl 6-hydroxyhexanoate

benzoyl chloride

→

title compound ( c )

benzyl 6-benzoyloxyhexanoate

溶剂

methylene chloride

反应条件

后处理

1. 1
   workup.ADDITIONThe reaction mixture was treated in the conventional manner
2. 2
   workup.DISTILLATIONwas distilled under reduced pressure (1 mmHg, 190°-215° C.)

实验过程

To a solution of benzyl 6-hydroxyhexanoate (b) (27.37 g) in methylene chloride were added 4-dimethyl amino pyridine (19.5 g) and benzoyl chloride (19.53 g), and the resultant mixture was stirred for 2 hours. The reaction mixture was treated in the conventional manner and was distilled under reduced pressure (1 mmHg, 190°-215° C.) to give the title compound (c).

来源