反应 #49941

反应方程式

N'-t-butyl-N-benzoylhydrazine

potassium carbonate

bromoethyl acetate

→

product

收率 9.4%

N-benzoyl-N'-t-butyl-N'-(ethoxycarbonyl)methylhydrazine

收率 9.4%

溶剂

water

ether

dimethylformamide

反应条件

后处理

1. 1
   其他the organic layer was separated
2. 2
   洗涤The organic layer was washed several times with water
3. 3
   干燥dried over magnesium sulfate
4. 4
   其他to afford an oil
5. 5
   其他Chromatographic purification

实验过程

N'-t-butyl-N-benzoylhydrazine (2.0 g), powdered potassium carbonate (5 g) and bromoethyl acetate (1.6 g) were stirred in dimethylformamide (20 ml) at 60° C. for 14 hours. The reaction mixture was diluted with water and ether, and the organic layer was separated. The organic layer was washed several times with water, dried over magnesium sulfate and rotavapped to afford an oil. Chromatographic purification gave the pure oil product (0.25 g).

来源