反应 #49068

反应方程式

D4

2-methyl-2-(1-pyrrolidinyl)propanenitrile

pyrrolidine

cyclopentanone

potassium cyanide

→

title compound

收率 76.0%

1-(1-Pyrrolidinyl)cyclopentanecarbonitrile

收率 76.0%

溶剂

water

反应条件

实验过程

The title compound (2.50 g, 76%) was prepared from pyrrolidine (1.42 g, 20 mmol), cyclopentanone (1.68 g, 20 mmol) and potassium cyanide (1.30 g, 20 mmol) in water (10 ml) in a similar manner to that described in D4. 1H NMR (CDCl3) δ: 1.80-1.90 (10H, m), 2.15 (2H, m), 2.71 (4H, m).

来源