反应 #487114

反应方程式

ethyl chloride

sodium

N-hydroxytetrahydrophthalimide

ethyl chloride

→

N-ethoxytetrahydrophthalimide

收率 81.0%

溶剂

methyl tert-butyl ether

反应条件

后处理

1. 1
   温度was maintained at 100° C
2. 2
   其他were separated

实验过程

In an autoclave 60 g of a 20 wt % solution of the sodium salt of N-hydroxytetrahydrophthalimide (0.063 mol), 20 ml of methyl tert-butyl ether and 5.0 g of ethyl chloride were mixed together. The mixture was heated to 100° C. After reaching this temperature the mixture was stirred for a further 5 hours while the temperature was maintained at 100° C. After 5 hours' reaction the excess ethyl chloride was blown out and the reaction mixture was discharged. The reaction mixture was composed of two liquid layers which were separated. The ether layer was analysed by gas chromatography. A yield of 81% of N-ethoxytetrahydrophthalimide (0.051 mol) was found.

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