反应 #487065
ord-f17162eee9fd4fa2a1cf4cb44ea995ed
反应方程式
2-indolylacetic acid
(2-methyl-3-indolyl)acetic acid
indole-3-butyric acid
(5-methoxyindol-3-yl)acetic acid
flavone-8-acetic acid
3-(3-indolyl)propionic acid
chlorambucil
3,4-(methylenedioxy)phenylacetic acid
3,4-(methylenedioxy)cinnamic acid
→
3-Indolylacetic acid
反应物
2-indolylacetic acid
(2-methyl-3-indolyl)acetic acid
—
3- or 2-indolylacrylic acid
indole-3-butyric acid
(5-methoxyindol-3-yl)acetic acid
—
(N-methyl)-2- or -3-indolylacetic acid
—
corticoid 21-carboxylic esters
flavone-8-acetic acid
—
2-acetic acid
—
5,6-dimethylxanthone 4-acetic acid
3-(3-indolyl)propionic acid
chlorambucil
3,4-(methylenedioxy)phenylacetic acid
3,4-(methylenedioxy)cinnamic acid
试剂
无
反应条件
详细条件
See reaction.notes.procedure_details.
后处理
- 1其他prepared from
实验过程
2-indolylacetic acid; (N-methyl)-2- or -3-indolylacetic acid; 3-(3-indolyl)propionic acid; 3- or 2-indolylacrylic acid (also (N-methyl)); (2-methyl-3-indolyl)acetic acid, 3,4-(methylenedioxy)phenylacetic acid; 3,4-(methylenedioxy)cinnamic acid; indole-3-butyric acid; (5-methoxyindol-3-yl)acetic acid; naphthyl-1- or -2-acetic acid; flavone-8-acetic acid; 5,6-dimethylxanthone-4-acetic acid (L. L. Thomsen et al.: Cancer Chemother, Pharmacol. 31, 151ff. (1992) demonstrate that the corticoid 21-carboxylic esters prepared from this could also have an antitumorigenic effect, likewise the abovementioned chlorambucil).