反应 #484418

ord-6710d937e459414291f1e8276b7a03df

反应方程式

CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](OC(=O)NCCN(C)C)CC[C@]4(C)[C@H]3CC[C@]12C.Cl
DC-Chol
CI
iodomethane
→
CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C
Cholesterol

反应物

—
3-β-[N(N′,N′,N′-trimethylethane)carbamoyl]cholesterol
—
quaternary ammonium
CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](OC(=O)NCCN(C)C)CC[C@]4(C)[C@H]3CC[C@]12C.Cl
DC-Chol
CI
iodomethane

试剂

无

反应条件

详细条件
See reaction.notes.procedure_details.

实验过程

3-β-[N(N′,N′,N′-trimethylethane)carbamoyl]cholesterol (TC-Chol), a quaternary ammonium derivative of Chol, was synthesized by methylation of DC-Chol with iodomethane.

来源

DOI: 10.6084/m9.figshare.5104873.v1专利: US06610321B2uspto-grants-2003_08