反应 #47736
ord-b51d7cb6b41e41718e3f39d76b7da4bc
反应方程式
Glutaric anhydride
3-ethynylaniline
→
product
收率 99.0%
4-(3-Ethynyl-phenylcarbamoyl)-butyric acid
收率 99.0%
反应条件
详细条件
See reaction.notes.procedure_details.
后处理
- 1其他was evaporated under reduced pressure
实验过程
Glutaric anhydride (215 mg, 1.9 mmol) was dissolved in anhydrous dichloromethane (7 ml) and followed by the addition of 3-ethynylaniline (200 mg, 1.7 mmol). The mixture was allowed to stir at room temperature for 6 hours before the solvent was evaporated under reduced pressure to provide the product as a white solid (363 mg, 99%);