反应 #47723

反应方程式

N2,4-diphenylpyridine-2,3-diamine

ethoxymethylene malononitrile

→

3.7-diphenyl-3H-imidazo[4,5-b]pyridine

收率 75.0%

溶剂

isopropanol

反应条件

后处理

1. 1
   温度refluxed for 6 hours
2. 2
   其他The solution was removed
3. 3
   其他was purified
4. 4
   其他to thereby produce a solid crystalline product at a yield of 75%

实验过程

0.70 mol of N2,4-diphenylpyridine-2,3-diamine and 2.56 mol of ethoxymethylene malononitrile were added in 10 ml of isopropanol, and refluxed for 6 hours. The solution was removed and was purified by using column chromatography to thereby produce a solid crystalline product at a yield of 75%.

来源