反应 #470424

反应方程式

4′,7-Dihydroxy-4-(4-methoxyphenyl)isoflav-3-ene

ethanol

4-Chlorobenzylamine

formaldehyde

→

title compound

收率 30.0%

4-(3-(4-Chlorobenzyl)-6-(4-methoxyphenyl)-2,3,4,8-tetrahydro-chromeno[6,7-e][1,3]oxazin-7-yl)phenol

收率 30.0%

反应条件

后处理

1. 1
   其他The resulting precipitate was collected

实验过程

4′,7-Dihydroxy-4-(4-methoxyphenyl)isoflav-3-ene (205 mg, 0.59 mmol) was dissolved in ethanol (1 ml). 4-Chlorobenzylamine (0.09 ml, 0.74 mmol) was added followed by formaldehyde solution (0.6 ml, 8.06 mmol, 37% wt.). The reaction stirred at room temperature for 3 days. The resulting precipitate was collected to afford the title compound (90 mg, 30%).

来源