反应 #470419

反应方程式

4′,7-Dihydroxyisoflav-3-ene

ethanol

4-Chlorobenzylamine

formaldehyde

→

title compound

收率 88.0%

4-(3-(4-Chlorobenzyl)-2,3,4,8-tetrahydrochromeno[6,7-e][1,3]oxazin-7-yl)phenol

收率 88.0%

反应条件

后处理

1. 1
   其他The white precipitate was collected

实验过程

4′,7-Dihydroxyisoflav-3-ene (506 mg, 2.11 mmol) was dissolved in ethanol (8 ml). 4-Chlorobenzylamine (0.33 ml, 2.70 mmol) was added followed by formaldehyde solution (2 ml, 0.03 mol, 37% wt.). The reaction was stirred at room temperature for 4 days. The white precipitate was collected to afford the title compound (748 mg, 88%).

来源