反应 #470418

反应方程式

7-Hydroxy-3′,4′-dimethoxy-8-methylisoflav-3-ene

ethanol

Benzylamine

formaldehyde

→

title compound

收率 15.0%

3-Benzyl-7-(3,4-dimethoxyphenyl)-10-methyl-2,3,4,8-tetrahydro-chromeno[6,7-e][1,3]oxazine

收率 15.0%

反应条件

后处理

1. 1
   其他The precipitate was collected

实验过程

7-Hydroxy-3′,4′-dimethoxy-8-methylisoflav-3-ene (155 mg, 0.52 mmol) was dissolved in ethanol (2.5 ml). Benzylamine (0.07 ml, 023 mmol) was added followed by formaldehyde solution (0.6 ml, 8.06 mmol, 37% wt.). The reaction was stirred at room temperature for 2 days. The precipitate was collected to afford the title compound (33 mg, 15%).

来源