反应 #470396

反应方程式

N-(2-nitrophenyl)biphenyl-2-amine

hydrogen

→

N1-(biphenyl-2-yl)benzene-1,2-diamine

溶剂

ethanol

反应条件

后处理

1. 1
   过滤The solution was filtered through Celite
2. 2
   其他to remove the catalyst, Celite
3. 3
   洗涤was washed with dichloromethane
4. 4
   其他the filtrate was evaporated
5. 5
   其他to yield a brown oil, 14.8 g (84%)
6. 6
   其他The product was used for the next step without further purification

实验过程

N-(2-nitrophenyl)biphenyl-2-amine (19.69 g, 67.8 mmol), 10% palladium on carbon (0.29 g, 0.27 mmol), and 150 mL of ethanol was added to a Parr hydrogenator bottle. The mixture was hydrogenated on a Parr hydrogenator until no more hydrogen was taken up by the solution. The solution was filtered through Celite to remove the catalyst, Celite was washed with dichloromethane, the filtrate was evaporated to yield a brown oil, 14.8 g (84%). The product was used for the next step without further purification.

来源