反应 #470389

反应方程式

2-isopropyl-N-(2-nitrophenyl)aniline

hydrogen

→

desired product

收率 99.3%

N1-(2-isopropylphenyl)benzene-1,2-diamine

收率 99.3%

溶剂

ethanol

反应条件

后处理

1. 1
   过滤The catalyst was filtered off through a Celite bed
2. 2
   其他The solvent was evaporated
3. 3
   其他The product was used for the next step without further purification

实验过程

2-isopropyl-N-(2-nitrophenyl)aniline (22.7 g, 89 mmol) and 10% palladium on carbon (0.6 g) were mixed with 150 mL of ethanol under nitrogen in a plastic coated hydrogenation vessel. The mixture was put on a par hydrogenator and reacted under 40 psi of hydrogen until there is no pressure drop. The catalyst was filtered off through a Celite bed. The solvent was evaporated. The product was used for the next step without further purification. 20 g of desired product was obtained.

来源