反应 #470368

反应方程式

sodium acetate

N-methoxymethyl-N-methylpyrrolidinium chloride

N-Methyl-N-Methoxymethylpyrrolidinium Chloride

→

desired product

N-Methoxymethyl-N-Methylpyrrolidinium Acetate

溶剂

methanol

反应条件

后处理

1. 1
   其他The mixture was reacted at room temperature for 1.5 hours
2. 2
   其他whereby the reaction was terminated
3. 3
   过滤The reaction mixture was filtered
4. 4
   浓缩the filtrate was concentrated
5. 5
   其他dried in a vacuum
6. 6
   workup.ADDITIONTo the residue was added 100 ml of dichloromethane
7. 7
   过滤followed by filtration with a membrane
8. 8
   过滤filter
9. 9
   浓缩concentration in a vacuum
10. 10
    其他drying

实验过程

A 9.46 g quantity of sodium acetate (product of Wako Pure Chemical Ind. Ltd.) was dissolved in 95 g of methanol, and 19.10 g of N-methoxymethyl-N-methylpyrrolidinium chloride was added to the solution. The mixture was reacted at room temperature for 1.5 hours, whereby the reaction was terminated. The reaction mixture was filtered, and the filtrate was concentrated and dried in a vacuum. To the residue was added 100 ml of dichloromethane, followed by filtration with a membrane filter, concentration in a vacuum and drying, affording 20.38 g of the desired product.

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