反应 #470365

反应方程式

sodium perchlorate

N-methoxymethyl-N-methylpyrrolidinium chloride

N-Methyl-N-Methoxymethylpyrrolidinium Chloride

→

desired product

N-Methoxymethyl-N-Methylpyrrolidinium Perchlorate

溶剂

ethyl alcohol

反应条件

后处理

1. 1
   其他The mixture was reacted at room temperature for 1.5 hours
2. 2
   其他whereby the reaction was terminated
3. 3
   过滤The resulting sodium chloride was filtered off
4. 4
   浓缩the filtrate was concentrated
5. 5
   其他dried in a vacuum
6. 6
   workup.DISSOLUTIONThe residue was dissolved in dichloromethane
7. 7
   过滤the solution was again filtered with a membrane
8. 8
   过滤filter
9. 9
   浓缩the filtrate was concentrated in a vacuum
10. 10
    其他dried

实验过程

A 5.91 g quantity of sodium perchlorate (product of Wako Pure Chemical Ind. Ltd.) was dissolved in 77 g of ethyl alcohol, and 7.99 g of N-methoxymethyl-N-methylpyrrolidinium chloride was added to the solution. The mixture was reacted at room temperature for 1.5 hours, whereby the reaction was terminated. The resulting sodium chloride was filtered off, and the filtrate was concentrated and dried in a vacuum. The residue was dissolved in dichloromethane, the solution was again filtered with a membrane filter, and the filtrate was concentrated in a vacuum and dried, giving 10.94 g of the desired product.

来源