反应 #470364

反应方程式

sodium carbonate

N-methoxymethyl-N-methylpyrrolidinium chloride

N-Methyl-N-Methoxymethylpyrrolidinium Chloride

→

desired product

N-Methoxymethyl-N-Methylpyrrolidinium Carbonate

溶剂

water

反应条件

后处理

1. 1
   其他The mixture was reacted at room temperature for 0.5 hour
2. 2
   其他whereby the reaction was terminated
3. 3
   浓缩The reaction mixture was concentrated
4. 4
   干燥dried in vacuum, and 100 ml of ethyl alcohol
5. 5
   workup.ADDITIONwas added to the residue
6. 6
   其他to remove insoluble sodium chloride
7. 7
   workup.DISSOLUTIONThe resulting product was dissolved in dichloromethane
8. 8
   过滤the solution was filtered with a membrane
9. 9
   过滤filter again
10. 10
    浓缩the filtrate was concentrated in a vacuum
11. 11
    其他dried

实验过程

A 1.60 g quantity of sodium carbonate (product of Wako Pure Chemical Ind. Ltd.) was dissolved in 18 g of deionized water, and 5.01 g of N-methoxymethyl-N-methylpyrrolidinium chloride was added to the solution. The mixture was reacted at room temperature for 0.5 hour, whereby the reaction was terminated. The reaction mixture was concentrated and dried in vacuum, and 100 ml of ethyl alcohol was added to the residue to remove insoluble sodium chloride. The resulting product was dissolved in dichloromethane, the solution was filtered with a membrane filter again, and the filtrate was concentrated in a vacuum and dried, giving 5.41 g of the desired product.

来源