反应 #465941

反应方程式

triphenylamine

DMF

phosphorus oxychloride

→

4-(N,N-diphenylamino)benzaldehyde

收率 81.0%

溶剂

water

反应条件

后处理

1. 1
   其他reaction for 5 hours
2. 2
   其他The reaction solution obtained
3. 3
   workup.STIRRINGby stirring for 1 hour
4. 4
   其他Thereafter, the precipitate formed
5. 5
   过滤was collected by filtration
6. 6
   洗涤washed with a mixture of ethanol/water (1:1)

实验过程

Into a three-necked flask, 101.4 g of triphenylamine and 35.5 ml of DMF (dimethylformamide) were placed, and 84.4 ml of phosphorus oxychloride was added dropwise thereto with stirring while cooling with ice water, and then the temperature was raised to 95° C. to carry out reaction for 5 hours. The reaction solution obtained was poured into 4 liters of warm water, followed by stirring for 1 hour. Thereafter, the precipitate formed was collected by filtration, and washed with a mixture of ethanol/water (1:1) to obtain 4-(N,N-diphenylamino)benzaldehyde in an amount of 91.5 g (yield: 81.0%).

来源