反应 #452424

反应方程式

N-(4-fluorobenzoyl)-4-nitroaniline

→

N-(4-fluoro-benzoyl)-4-aminoaniline

收率 79.0%

溶剂

tetrahydrofuran

反应条件

后处理

1. 1
   过滤The reaction mixture was then filtered
2. 2
   浓缩the filtrate concentrated under reduced pressure

实验过程

A mixture of 32.25 gm (124 mMol) N-(4-fluorobenzoyl)-4-nitroaniline and 3.2 gm platinum on carbon in 500 mL tetrahydrofuran was hydrogenated at room temperature for 18 hours with an initial pressure of 60 p.s.i. The reaction mixture was then filtered and the filtrate concentrated under reduced pressure to give 22.45 gm (79%) of N-(4-fluoro-benzoyl)-4-aminoaniline.

来源