反应 #4473

反应方程式

product

1,3-Cyclohexanedione mono(4-bromophenylhydrazone)

water

→

title compound

6-Bromo-1,2,3,9-tetrahydro-4H-carbazol-4-one

溶剂

acetic acid

反应条件

后处理

1. 1
   温度The mixture was cooled
2. 2
   过滤the resulting solid filtered off
3. 3
   其他dried (0.95 g)
4. 4
   其他Purification by flash chromatography (E)

实验过程

The product of Stage (i) (1.5 g) was heated under reflux with dry zinc chloride (16 g) in glacial acetic acid (75 ml) for 24 h. The mixture was cooled, poured into water (200 ml), and the resulting solid filtered off and dried (0.95 g). Purification by flash chromatography (E) gave the title compound as a solid (125 mg). T.l.c. (F), Rf 0.65

来源