反应 #44352

反应方程式

Morpholine

4-bromo-2,5-difluoro-benzenesulfonyl chloride

→

sub-title compound

4-[(4-bromo-2,5-difluorophenyl)sulfonyl]-morpholine

溶剂

dichloromethane

反应条件

后处理

1. 1
   其他quenched with water
2. 2
   干燥The organic phase was dried (MgSO4)
3. 3
   浓缩concentrated in vacuo

实验过程

Morpholine (0.16 ml) was added to a stirred solution of 4-bromo-2,5-difluoro-benzenesulfonyl chloride (0.18 g) in dichloromethane (6 ml) under nitrogen. The reaction mixture was stirred overnight and then quenched with water. The organic phase was dried (MgSO4) and concentrated in vacuo to give the sub-title compound as a white solid (200 mg).

来源