反应 #443317

反应方程式

oxindole

5-methylthiophene-2-carboxaldehyde

→

title compound

收率 99.0%

3-[(2-Methylthien-5-yl)methylene]-2-indolinone

收率 99.0%

溶剂

ethanol

反应条件

后处理

1. 1
   温度After cooling
2. 2
   过滤the precipitate was filtered
3. 3
   洗涤washed with cold ethanol
4. 4
   其他dried

实验过程

A reaction mixture of 134.0 mg of oxindole, 151.42 mg of the 5-methylthiophene-2-carboxaldehyde, and 3 drops of piperidine in 2 mL of ethanol was stirred at 90° C. for 3 h. After cooling, the precipitate was filtered, washed with cold ethanol, and dried to yield 237.8 mg (99%) of the title compound as a yellow solid.

来源