反应 #44146

反应方程式

(5-bromo-2-fluorophenyl)acetaldehyde

2-methyl-5-(1-piperazinyl)quinoline

sodium triacetoxyborohydride

→

title compound

收率 95.0%

5-{4-[2-(5-Bromo-2-fluorophenyl)ethyl]-1-piperazinyl}-2-methylquinoline

收率 95.0%

反应条件

实验过程

The title compound was prepared in 95% yield from (5-bromo-2-fluorophenyl)acetaldehyde (0.98 g), 2-methyl-5-(1-piperazinyl)quinoline (0.51 g) and sodium triacetoxyborohydride (0.95 g) according to the procedure described for Example 131.

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