反应 #4361

反应方程式

ethyl (2,4-dichloro-5-fluoro-3-nitrobenzoyl)-acetate

triethyl orthoformate

acetic anhydride

→

Ethyl 2-(2,4-dichloro-5-fluoro-3-nitro-benzoyl)-3-ethoxyacrylate

反应条件

后处理

1. 1
   浓缩The mixture is then concentrated in vacuo and 270 g of ethyl benzoyl-ethoxy-acrylate
2. 2
   其他are obtained as an oily residue

实验过程

244.8 g of ethyl (2,4-dichloro-5-fluoro-3-nitrobenzoyl)-acetate are heated at 150°-160° C. with 166 g of triethyl orthoformate and 185 g of acetic anhydride for 3 hours. The mixture is then concentrated in vacuo and 270 g of ethyl benzoyl-ethoxy-acrylate are obtained as an oily residue.

来源