反应 #4336

反应方程式

2,5-dibromo-4-nitroaniline

compound B

2,5-dibromo-4-nitroaniline

ethanolamine

→

2-β-hydroxyethylamino-4-amino-5-bromonitrobenzene

溶剂

ethanol

反应条件

后处理

1. 1
   workup.ADDITIONhave been added
2. 2
   温度The mixture is heated
3. 3
   温度After cooling
4. 4
   其他dilution of the reaction mixture with 100 ml of iced water, the expected product precipitates

实验过程

0.02 mole (5.92 g) of 2,5-dibromo-4-nitroaniline (compound B) is added to 15 ml of 96° ethanol to which 12 ml of ethanolamine have been added. The mixture is heated in refluxing alcohol for 6 h 30 min. After cooling and dilution of the reaction mixture with 100 ml of iced water, the expected product precipitates.

来源