反应 #433598

反应方程式

3,4-Dichloro-6-fluoroaniline

4-chloro-7-fluoro-6-nitroquinazoline

→

4-[(3,4-dichloro-6-fluorophenyl)amino]-7-fluoro-6-nitroquinazoline

收率 78.0%

溶剂

iso-propylalcohol

反应条件

后处理

1. 1
   过滤After filtration

实验过程

3,4-Dichloro-6-fluoroaniline (1 equivalent) was reacted with 4-chloro-7-fluoro-6-nitroquinazoline (3.5 equivalents), in iso-propylalcohol. After filtration, 4-[(3,4-dichloro-6-fluorophenyl)amino]-7-fluoro-6-nitroquinazoline was obtained in 78% yield.

来源