反应 #43083

反应方程式

(3-Amino-propyl)-carbamic acid tert-butyl ester

benzoyl choride

triethylamine

→

(3-Benzoylamino-propyl)-carbamic acid tert-butyl ester

溶剂

methylene chloride

反应条件

后处理

1. 1
   洗涤The reaction mixture was washed with 1 N HCl
2. 2
   其他the solvent removed
3. 3
   其他to give product

实验过程

(3-Amino-propyl)-carbamic acid tert-butyl ester (1.6 g) was treated with with benzoyl choride (1.1 eq.) and triethylamine (1.5 eq) in methylene chloride (50 mL). The reaction mixture was washed with 1 N HCl, sat, NaHCO3, and sat NaCl and the solvent removed to give product. LC-MS showed the product had the expected M+H+ of 279.

来源