反应 #411183

反应方程式

Morpholine

1,4-butane sultone

→

title compound

收率 18.0%

4-Morpholin-4-yl-butane-1-sulfonic acid

收率 18.0%

溶剂

isopropanol

反应条件

后处理

1. 1
   其他The white precipitate that had formed
2. 2
   过滤was filtered
3. 3
   其他dried

实验过程

Morpholine (3.56 g) was dissolved in isopropanol (25 ml) and treated with 1,4-butane sultone (5.58 g) at 10° C. The reaction mixture was allowed to warm to room temperature and stirred for 3 days. The white precipitate that had formed was filtered and dried to give the title compound (1.64 g). Mass spec MH+ (found) 224 MH+ (calc) 224.

来源