反应 #409980

反应方程式

1-oxyl-4-hydroxy-2,2,6,6-tetramethylpiperidine

ethylbenzene

→

off-white solid

收率 45.3%

1-(1-Phenylethyl)oxy-4-hydroxy-2,2,6,6-tetramethylpiperidine

收率 45.3%

反应条件

后处理

1. 1
   其他The volatiles are removed in vacuo
2. 2
   其他the residue is triturated with diethyl ether
3. 3
   过滤The precipitate of 1,4-dihydroxy-2,2,6,6-tetramethylpiperidine is collected by filtration

实验过程

A mixture of 17.23 g (0.10 mol) of 1-oxyl-4-hydroxy-2,2,6,6-tetramethylpiperidine and 106.17 g (1.0 mol) of ethylbenzene under a nitrogen atmosphere is heated at 133° C. for 26 hours. The volatiles are removed in vacuo and the residue is triturated with diethyl ether. The precipitate of 1,4-dihydroxy-2,2,6,6-tetramethylpiperidine is collected by filtration to give 12.57 g of an off-white solid.

来源