反应 #4078

反应方程式

N-cyclohexyl-4-nitrosoaniline

NaOH

n-hexanol

→

N-cyclohexyl-p-phenylenediamine

反应条件

后处理

1. 1
   其他equipped with stirrer, condenser
2. 2
   温度thermometer, and heated
3. 3
   温度Heating
4. 4
   其他to rise to 115° C.
5. 5
   workup.ADDITIONdropped, within 10 minutes, to 100° C
6. 6
   温度With the application of heat
7. 7
   温度a temperature of 90°-95° C. was maintained for 30 minutes

实验过程

51.0 g (0.25 mole) N-cyclohexyl-4-nitrosoaniline, 20.0 g (50%) NaOH and 135 g n-hexanol were charged to a 0.5 liter three-necked round bottom flask equipped with stirrer, condenser and thermometer, and heated while stirring to 95° C. until the development of an exotherm was observed. Heating was discontinued, the reaction temperature continued to rise to 115° C. and then dropped, within 10 minutes, to 100° C. With the application of heat, a temperature of 90°-95° C. was maintained for 30 minutes. The reaction mixture contained no unreacted nitroso compound. The yield of the product was 64 wt. %; m.p. 59°-61° C.

来源