反应 #4069

反应方程式

N-bromosuccinimide

methyl phenylacetate

→

title compound

收率 93.1%

Methyl Bromo-Phenylacetate

收率 93.1%

溶剂

carbon tetrachloride

反应条件

后处理

1. 1
   温度to reflux
2. 2
   温度refluxed for about 12 hours
3. 3
   过滤filtered
4. 4
   浓缩The filtrate was concentrated by evaporation under vacuum

实验过程

In this example, a mixture containing 5.93 g of N-bromosuccinimide, 5.0 g of methyl phenylacetate; and a catalytic amount (about 0.1 g) of benzoyl peroxide in 50 ml of carbon tetrachloride was warmed to reflux and then refluxed for about 12 hours. The mixture was then cooled to about 0° C. and filtered. The filtrate was concentrated by evaporation under vacuum affording 7.1 g of the title compound as an oil.

来源