反应 #40369

ord-5bbcde2c94ff44219208d4f11cce28a3

反应方程式

CC(C)c1ccc(CCl)cc1
4-isopropylbenzyl chloride
CC(C)=O
acetone
CC(C)c1ccc(CC(C)(C)O)cc1
compound
CC(C)c1ccc(CC(C)(C)O)cc1
1-(4-isopropylphenyl)-2-methylpropan-2-ol

反应条件

详细条件
See reaction.notes.procedure_details.

后处理

  1. 1
    其他The reaction of a Grignard compound

实验过程

The reaction of a Grignard compound, prepared from 20 g (119 mmol) 4-isopropylbenzyl chloride, with 11.4 mL (155 mmol) acetone yields the target compound as a colorless oil. Yield: 13.0 g (57%); mass spectrometry: [M+H]+=193.

来源

DOI: 10.6084/m9.figshare.5104873.v1专利: US07727984B2uspto-grants-2010_06